Scientists say that to protect the aging brain from Alzheimer’s with an old solution – Lithium
In the nearly ten new discovery in the action of doing, researchers in Harvard Medical School said that they could open the myzheimer’s secrets and brain aging – Lithium humble.
The Lithium is well-known as the Mood Stabilizer Stabilizer given to people with breathing problems and depression. It was accepted by the US Food Food and Drug Administration in 1970, but were used by doctors to treat the disruption of the mood for about decades earlier.
Now, first, researchers have shown that Lithium naturally exists in smaller numbers and that the cells need to work normally – like vitamin C or iron. It also seems that it plays an important role in keeping the life of the brain.
In a series of tests test reported on Wednesday in Journal, Harvard Researchers and Harvard’s universities found that Libithium decrease in normal mice caused their brain caused their brain caused their brain caused their brain caused their brain caused their brain caused their brain caused their brain caused their aging.
In a special order to promote the same brain types, the infection of Libheimer, a nutritional food has been restored to the construction of adhesive proteins that have the symptoms of disease. It also continued to lose memory.
Keeping ordinary levels of Lithium in celebration as age, however, protects them from alzheimer’s flexibility.
Once a more study supports findings, it can open the new treatment department and diagnostic surveys, which affecting 6.7 million adults in the United States, according to disease prevention centers.
The Vision that includes Alzheimer’s Disease
This study provides theory that includes clarifying the majority of puzzle scientists who were trying to be accompanied by decades.
“It is a common practice that leads to the dementia of the brain multisaystem precursors,” said Dr Bruce Yankner, Professor of Genetics in Harvard Medical School, who led the study. “It will take too many science to find that this is the usual way … or one of several ways,” in Alzheimer’s, added. “Information is very wonderful.”
In the relationship published in nature, Dr. Ashley Bush, a neuroscience scholar guding the Melbourne Demector Reapia Center in Australia in Australia, “said the strong researchers that Lithium actually contributed to Lithium brain.” He was not involved in the meeting.
Examining the brain and animal tissue, which is found that the divids appear Lithium Alzheimer patients – including, including the most common type of body, as well as the form that is often exposed. This bleeding the Lithium are available nearby cells, including important scavengers known as a microllia.
When the brain is healthy and works typically, the microglia is rubble of waste, deleting the Beta Amyloid before accumulating and can cause injuries. In group exams, the microllla from the sins of the undisputed lilium-discing showed a reduced ability to flood and violated the Beta Amyloid.
Yankner believes this creates the submission of the floor. Beta Amyloid Sooks Sooks increases increase in Lithium, which continues to disabilities the elimination of the erase brain.
He and his colleagues checked the different Playumi computers and received one – Lithium and Totate – that does not bolster the Amyloid Beta.
When they give Lithium rats with the symbalms of the mice with Alzheimer’s symptoms, these changes were returned back: Beta Amyloid Tangles and TAU tangles were taunting. The lithium treated with Lithium is unable to wander in mazes and learn to identify new things, and those who receive a pardos do not show changes in their fightings and thinking.
Don’t try this at home
Its nature, the lithium is something, a soft, white iron that connects and other things to build computers and salts. Natural now in this area, including food and water.
Lithium is a soft, white-white-existing white is present in food and water. – Carla Gottgens / Bloomberg / Getty Photos
Scientists have never completely known how to improve feelings – only. The original formula of the 7up soda installed is Lithium – it is called 7up Linelated Lemon Soda – and tend to be a Hangover and Mood Lifter “at a hospital or hospital.” Some known treasures of minerals of minerals in Lithium was demanded by their power.
Nevertheless, people who take the lithium doses – higher than doses used in new research – sometimes it can have thyroid or kidneys.
Average test provided by the low lithium and Rotate doses showed signs of damage.
That is encouraging, said Yankner, but it does not mean that people should try to take Lithium suppliers themselves.
“The mouse is no human. No one should take anything based on mouse studies,” said Yankner.
“The lithium treatment we have is in the celebration, and requires repetition of people. We need to find the right dose from people,” add.
Normal prices at Lithium in our bodies, and focus given rats, are less – about 1,000 times less damaged by bipolar disorder, yankner’s notorder notes.
The yanker said she hoped for the lithium’s salt tests to start soon. No one of his financial writers have a financial interest in the research results, he said.
The National of Health facilities were a great deal of study, as well as allowances from private bases.
“The Support of NIH was completely criticized in this work,” said Yankner.
Evidence has created the Tiny role in the aging
The new research includes previous training courses that Foothoam may be important to Alzheimer’s. The great Denmark study of the year was receiving the top of the Lithium in the water and would have been diagnosed with the concepts compared to tapes. Another large study published in 2022 from the United Kingdom found that people put Lobithium likely likely to have the group under control of Alzheimer’s, suggesting the effect of protecting medication.
But the use of lithium in Mithiary has made it a type of throwing as a treating, says Yankner. No one saw it would be important to the average body body.
That happens in part because the number of Lithium often travels in the body is very small, it couldn’t make up to recently. The yankner and his team had to make a stretching technology to measure.
In the first stage of research, scientists have examined the brain tissue and the old patients of patients collected by Brain Bank at the Rush University to track 27 levels. Some patients had no history of memory problem, while others had the first memory drop and Alzheimer’s. While there was no change at many metals they measure, Lenithium was different. Lithium levels are regularly divided into patients with discreetly discreet or alzheimer’s unconditions with those who have regular brain work. Patients The patient Alzheimer’s Disease refers to increased levels in Zinc and decreases the brass levels, which scientists have seen earlier.
Regularly receiving Lithium levels are low in the branches of people who have lost limited memory of a smoker, said Yankner.
“At first, unquerionably, we were praying about it because it was unexpected,” said Yankner.
But they have proposed or viewing samples from other brain banks in the Massachusetts General Hospital, Duke and Washington universities.
“We wanted to know if this drop was on a natural purpose, so we called the test law where we could take Lithium especially on mice foods and see what happened,” said Yankner what’s happening.
When they support rats with low lipwey food, simply get rid of their natural levels by 50%, their brain has improved quickly in Alzheimer’s.
“Neurons are starting to be corrupted. The brain cells are in accordance with the increased wild and the worst energy-ups of Neurons, and it looked like an advanced patient of Alzheimer,” said Yankner.
The team also received four-profiles that showed unclassic mice and people with Alzheimer’s seemed similar.
The investigators then began to check that this dropped from the lithium can happen. The yanker said in the first stages than a decrease in Lithium brain in the brain in the blood. They have not known them well how it happened or why, but they may come from a variety of things including foods, and genes and natural resources.
A great Source of Leqium to many people’s food. Some of the greenhius foods are the green vegetables, nuts, legumes and spices like turmeric and tumor. Some minerals are also rich.
In other words, the Yankner said, many foods that have been proved to be healthy and reduce the risk of dementia can benefit from their lithium content.
“You know, some times a person finds the science that things can have an impact, and think well why, but after that they do not completely hurt why,” he said.
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