Crisp Gene-Editing Technology He has shown its power of the changes in recent years: It is used to treat unchanging diseases, harmonizing plants to overthrow climate change, or even change the spiderwear. But the greatest hope that this technology will help you find a solution to the global disease, such as diabetes. New points to study in that option.
For the first time, researchers are successful in achieving pancreatic cells organized in the pancreatics for a type 1 diabetes, autoimmune disease where the immune system attacks insulin. Apart from insulin, the body cannot control blood sugar. If measures are not taken to manage glucose levels in another way (usually, injecting insulin), this can result in injury and tests – especially heart, kidneys and eyes. About 9.5 million people worldwide have 1 diabetes.
In this test, organized cells produced insulin for months after the installation, without the need to make any need to take any additional drugs to stop their bodies. The Crispp technology allowed researchers to allow genetically modified cells with camouflage to avoid detection.
Research, published last month in the New England Journal of Medicine, Details of the step on step. First, the pancreatic cells is taken from the deceased supplier without diabetes, and be replaced by the Crispriciki Califer Cells, Professor in the Cedars-Nai Medical Center California and Cofoi Medical Center Biotechnology, the company that creates this treatment.
Streamed cells and then installed in the pre-patient body, and 12 weeks, the symptoms were found. (Next report from Sana Biotechnology notes that cells included in the influence of the patient’s immune system after six months.)
The testing runs as part of the research that worked well-in-handed cells: Funcut cells in response to Glucose levels, representing the key to sugar regulations without the need for diabetes injections. Four negative events were recorded during the patient’s follow-up, but not one of them had difficulty or contacted with modified cells.
The final policy of researchers to organize the structure of the body to separate stem-competent production cells and separate other types of cells within the body of ithilin. “The benefits of hypoimone stem cells that when stem cells increases and created new cells, new cells,” Schrepfer a hypoimmune, “Sinai q + earlier this year.
Traditionally, transfer foreign cells to the patient necessary to pressure the patient’s immune system to avoid rejection. This carries great risks: infection, poison, and long-term problem. “To see patients killed because of the difficult dispositions or problems from Immunosuppression, and I decided to focus on my work.
Although the study marks a milestone in search of the treatment of type 1 diabetes, it is important to recognize that this study is involved in a short-term collapse – it is not enough for the patient to not need to control their insulin. The journal of a journal journal is a type of journal and we say that some specific research groups have failed in its efforts to ensure that the way of Sana provides organized cells through the ability to avoid the immune system.
The baby will be seeking to make many clinics first year. Besides concerning the criticism and limitations of the current learning, artificial cells that are transformed to prevent the immune system to open the most promising universe in renewal drugs.
This story at the beginning appeared -Ome en español and translated from Spain.
